Primary Identifier | MGI:1916712 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 69462 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Acts upstream of or within keratinocyte proliferation. Predicted to be located in extracellular space. Predicted to be active in plasma membrane. Used to study palmoplantar keratosis. Orthologous to human SLURP2 (secreted LY6/PLAUR domain containing 2). PHENOTYPE: Homozygous knockout results in hyperkeratosis of the paw skin, slow postnatal weight gain and reduced body fat mass. [provided by MGI curators] |