| Primary Identifier | MGI:98857 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 22122 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GDP-L-fucose synthase activity and isomerase activity. Involved in 'de novo' GDP-L-fucose biosynthetic process. Acts upstream of or within T cell mediated cytotoxicity. Is active in cytosol. Orthologous to human GFUS (GDP-L-fucose synthase). PHENOTYPE: Homozygotes for a targeted null mutation frequently die in utero, while survivors are smaller than normal, show colon abnormalities, have reduced fertility, and frequently die before weaning. Heterozygotes also show some embryonic loss. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
