Primary Identifier | MGI:1915209 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 67959 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome; mRNA splice site recognition; and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cell junction and nucleoplasm. Predicted to be part of ribonucleoprotein complex. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human PUF60 (poly(U) binding splicing factor 60). PHENOTYPE: Mice homozygous for a null allele die prior to E4.5. Mice heterozygous for a null allele exhibit with increased organ or bone marrow invasion with poor prognosis in the presence of a Trp53 null allele. [provided by MGI curators] |