| Primary Identifier | MGI:1913695 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 66445 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heme binding activity; metal ion binding activity; and ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c and response to glucagon. Located in mitochondrion. Part of respiratory chain complex III. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; heart; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). PHENOTYPE: Mice homozygous for a knock-out allele show small embryo size, embryonic growth retardation, abnormal epiblast and embryonic-extraembryonic boundary morphology, and complete embryonic lethality by E9.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
