| Primary Identifier | MGI:1919277 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 72027 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and zinc ion transmembrane transporter activity. Involved in intracellular zinc ion homeostasis. Acts upstream of or within cellular response to zinc ion starvation. Located in apical plasma membrane and recycling endosome membrane. Is expressed in several structures, including alimentary system; early embryo; extraembryonic component; genitourinary system; and integumental system. Used to study acrodermatitis enteropathica. Human ortholog(s) of this gene implicated in acrodermatitis enteropathica. Orthologous to human SLC39A4 (solute carrier family 39 member 4). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic letahlity around E10. Mice heterozygous for a null allele exhibit developmental defects similar to the teratology of zinc deficiency. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
