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Protein Coding Gene : Lgals2 lectin, galactose-binding, soluble 2
Primary Identifier  MGI:895068 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  107753
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable carbohydrate binding activity and galactoside binding activity. Involved in positive regulation of inflammatory response. Predicted to be part of galectin complex. Is expressed in yolk sac endoderm. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human LGALS2 (galectin 2).
PHENOTYPE: Mice homozygous for a knockout allele exhibit altered leukocyte numbers, increased susceptibility to type IV hypersensitivity reaction, enhanced humoral immune response, increased colon mucin and increased spleen red pulp. [provided by MGI curators]
  • synonyms:
  • 2200008F12Rik,
  • AI324147,
  • expressed sequence AI324147,
  • MGI:1913785,
  • RIKEN cDNA 2200008F12 gene,
  • lectin, galactose-binding, soluble 2,
  • Lgals2,
  • MGI:2145981
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