Primary Identifier | MGI:2146207 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 106039 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Involved in Golgi to plasma membrane transport and protein localization to ciliary membrane. Acts upstream of or within positive regulation of protein catabolic process. Predicted to be located in Golgi apparatus; early endosome; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in trans-Golgi network. Is expressed in several structures, including genitourinary system; gut; nervous system; respiratory system; and white fat. Orthologous to human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1). PHENOTYPE: Mice homozygous for a gene-trapped allele display decreased birth weight, slow postnatal weight gain, hypoglycemia, increased plasma levels of acid hydrolases, and partial neonatal lethality. [provided by MGI curators] |