| Primary Identifier | MGI:105393 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 13404 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA strand exchange activity. Involved in double-strand break repair involved in meiotic recombination and double-strand break repair via homologous recombination. Acts upstream of or within germ cell development; meiosis I; and ovarian follicle development. Located in chromosome, telomeric region and lateral element. Is active in site of double-strand break. Is expressed in gonad. Used to study Sertoli cell-only syndrome. Orthologous to human DMC1 (DNA meiotic recombinase 1). PHENOTYPE: Homozygotes for targeted mutations are sterile with failure of homologous pairing in meiotic prophase in males and disrupted oogenesis in embryonic females with absence of germ cells in the adult ovary. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
