Primary Identifier | MGI:109443 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 14904 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activity and nucleic acid binding activity. Predicted to be involved in GTP metabolic process; positive regulation of mRNA catabolic process; and translation. Predicted to be located in cytosol. Predicted to be part of cytoplasmic exosome (RNase complex). Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human GTPBP1 (GTP binding protein 1). PHENOTYPE: Homozygous mice for a targeted null mutation were viable and fertile with no obvious morphological or behavioral defects. In addition, no defects in macrophage function were observed. [provided by MGI curators] |