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Protein Coding Gene : Nptxr neuronal pentraxin receptor
Primary Identifier  MGI:1920590 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  73340
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein phosphatase binding activity. Involved in neuron projection development; neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of postsynaptic specialization assembly. Located in plasma membrane. Is active in glutamatergic synapse. Is expressed in female associated reproductive structure; limb; male associated reproductive structure; and renal vasculature. Orthologous to human NPTXR (neuronal pentraxin receptor).
PHENOTYPE: Mice homozygous for a null mutation of this gene display a mild alteration in retinal ganglion cell innervation but are fertile with no obvious behavioral abnormalities. [provided by MGI curators]
  • synonyms:
  • NPR,
  • MGI:1921368,
  • 1200009K17Rik,
  • Nptxr,
  • DNA segment, Chr 15, Brigham & Women's Genetics 0580 expressed,
  • NPCD,
  • expressed sequence AI785356,
  • MGI:106317,
  • MGD-MRK-34009,
  • neuronal pentraxin receptor,
  • 1700036C17Rik,
  • MGI:2146019,
  • MGI:2146057,
  • AI452369,
  • RIKEN cDNA 5730406O18 gene,
  • MGI:1921988,
  • RIKEN cDNA 1700036C17 gene,
  • expressed sequence AI452369,
  • AI785356,
  • D15Bwg0580e,
  • 5730406O18Rik
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