| Primary Identifier | MGI:2443584 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 214669 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables promoter-specific chromatin binding activity. Acts upstream of or within several processes, including ectoderm development; stem cell differentiation; and stem cell proliferation. Located in nucleus. Is expressed in several structures, including blastocyst; early embryo; genitourinary system; gut; and immune system. Orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit failure of the inner cell mass to form a normal primitive ectoderm capable of gastrulation leading to abnormal embryo development, embryonic growth arrest, and lethality during organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
