| Primary Identifier | MGI:1926179 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 78929 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in centrosome and nucleoplasm. Predicted to be part of RNA polymerase III complex. Is expressed in several structures, including alimentary system; limb; nervous system; respiratory system; and sensory organ. Used to study primary ovarian insufficiency. Orthologous to human POLR3H (RNA polymerase III subunit H). PHENOTYPE: Mice homozygous for a null allele die before E10. Mice with a point mutation (p.D50G) show delayed pubertal development, with late first estrus or preputial separation, decreased fertility later in life, small litter size and decreased antral and primary follicles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
