| Primary Identifier | MGI:98962 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 22422 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemoattractant activity involved in axon guidance and frizzled binding activity. Involved in several processes, including Wnt signaling pathway, planar cell polarity pathway; nervous system development; and stem cell development. Acts upstream of or within several processes, including blood vessel morphogenesis; kidney development; and respiratory system development. Located in cell surface. Is expressed in several structures, including central nervous system; early conceptus; embryo ectoderm; genitourinary system; and sensory organ. Orthologous to human WNT7B (Wnt family member 7B). PHENOTYPE: Homozygous null embryos die at midgestational stages due to placental abnormalities involving the fusion of the chorion and allantois. Mice homozygous for a truncated allele display neonatal lethality, respiratory failure, and lung hemorrhage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
