| Primary Identifier | MGI:2675256 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 223780 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of heart rate; and regulation of blood pressure. Predicted to act upstream of or within positive regulation of angiogenesis. Predicted to be located in extracellular region. Is expressed in ductus deferens; epididymis; and esophagus. Orthologous to human ADM2 (adrenomedullin 2). PHENOTYPE: Mice homozygous for a null allele exhibit shrinkage of the brush border, perivascular cuffing and vacuole degeneration in the lungs and kidney, macrophage infiltration in the liver, increased vascular leakage, and increased susceptibility to surgery-induced sepsis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
