| Primary Identifier | MGI:1920212 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 72962 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables thymidine phosphorylase activity. Involved in dTMP catabolic process. Predicted to be active in cytosol. Is expressed in alimentary system; axial skeleton; central nervous system; hindlimb; and retina. Used to study mitochondrial DNA depletion syndrome 1. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; mitochondrial DNA depletion syndrome 1; mitochondrial encephalomyopathy; pancreatic cancer; and transitional cell carcinoma. Orthologous to human TYMP (thymidine phosphorylase). PHENOTYPE: Mice homozygous for a null allele exhibit reduced thymidine phosphorylase activity and increased thymidine levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
