| Primary Identifier | MGI:1349467 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 26874 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and protein dimerization activity. Involved in several processes, including fatty acid catabolic process; negative regulation of biosynthetic process; and positive regulation of fatty acid metabolic process. Acts upstream of or within response to bacterium. Located in peroxisome. Is expressed in several structures, including alimentary system; hemolymphoid system; limb; nervous system; and sensory organ. Orthologous to human ABCD2 (ATP binding cassette subfamily D member 2). PHENOTYPE: Mice homozygous for a disruption in this gene exhibit a late-onset cerebellar and sensory ataxia, loss of Purkinje cells, dorsal root ganglia cell degeneration, axonal degeneration in the spinal cord, and an accumulation of very long chain fatty acids. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
