Primary Identifier | MGI:2660628 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 223838 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metalloendopeptidase activity. Acts upstream of or within several processes, including extracellular matrix organization; negative regulation of apoptotic process; and positive regulation of melanocyte differentiation. Located in extracellular space. Is expressed in several structures, including incisor; integumental system; neural tube; tongue muscle; and trunk mesenchyme. Orthologous to human ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20). PHENOTYPE: Mice homozygous for spontaneous or ENU-induced mutations exhibit abnormal coat/hair pigmentation, including a typical white belt phenotype. [provided by MGI curators] |