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Protein Coding Gene : Nell2 NEL-like 2

Primary Identifier  MGI:1858510 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  54003
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables identical protein binding activity. Involved in commissural neuron axon guidance and fertilization. Located in extracellular region. Is expressed in several structures, including alimentary system; autopod; central nervous system; limb mesenchyme; and sensory organ. Orthologous to human NELL2 (neural EGFL like 2).
PHENOTYPE: Homozygous null mice display enhanced long term potentiation in the dentate gyrus of the hippocampus. Male mice homozygous for a null allele exhibit infertility, impaired binding of sperm to zona pellucida, and impaired sperm migration in female genital tract. [provided by MGI curators]
  • synonyms:
  • Nell2,
  • A330108N19Rik,
  • R75516,
  • mel91,
  • RIKEN cDNA A330108N19 gene,
  • NEL-like 2,
  • MGI:2444983,
  • expressed sequence R75516,
  • MGI:2146325

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For