Primary Identifier | MGI:1858510 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 54003 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in commissural neuron axon guidance and fertilization. Located in extracellular region. Is expressed in several structures, including alimentary system; autopod; central nervous system; limb mesenchyme; and sensory organ. Orthologous to human NELL2 (neural EGFL like 2). PHENOTYPE: Homozygous null mice display enhanced long term potentiation in the dentate gyrus of the hippocampus. Male mice homozygous for a null allele exhibit infertility, impaired binding of sperm to zona pellucida, and impaired sperm migration in female genital tract. [provided by MGI curators] |