Primary Identifier | MGI:107445 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 223843 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including G2/M transition of mitotic cell cycle; epidermal growth factor receptor signaling pathway; and neural precursor cell proliferation. Is expressed in several structures, including central nervous system; limb; limb bud; sensory organ; and tooth mesenchyme. Orthologous to human DBX2 (developing brain homeobox 2). PHENOTYPE: Mice homozygous or heterozygous for a null allele exhibit partial preweaning lethality, but normal skeleton phenotype. [provided by MGI curators] |