Primary Identifier | MGI:2145995 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 105827 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of synapse assembly. Predicted to be located in nucleus and plasma membrane. Predicted to be active in membrane. Is expressed in several structures, including brain; branchial arch; cranial ganglion; genitourinary system; and retina. Orthologous to human AMIGO2 (adhesion molecule with Ig like domain 2). PHENOTYPE: Homozygous null mice exhibit starburst amacrine cell and rod bipolar cell dendrite arbor expansion and enhanced direction selectivity of direction-selective ganglion cell responses to starburst amacrine cell signals. [provided by MGI curators] |