Primary Identifier | MGI:1328363 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 12455 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; nucleic acid binding activity; and protein kinase binding activity. Predicted to be involved in positive regulation by host of viral transcription and positive regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within protein phosphorylation. Located in nucleus. Is expressed in several structures, including central nervous system; early embryo; gonad; hemolymphoid system gland; and limb. Orthologous to human CCNT1 (cyclin T1). PHENOTYPE: Mice homozygous for a hypomorphic allele do not express AIRE-responsive genes in the thymus and display lymphocytic infiltration of lacrimal and salivary glands. [provided by MGI curators] |