| Primary Identifier | MGI:1913370 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 66120 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding and regulation of transcription by RNA polymerase II. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including craniocervical region bone; incisor; liver lobe; pancreas tip epithelium; and thoracic segment skeleton. Orthologous to human FKBP11 (FKBP prolyl isomerase 11). PHENOTYPE: Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
