Primary Identifier | MGI:108411 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 19082 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including adenyl ribonucleotide binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to contribute to AMP-activated protein kinase activity. Involved in import into nucleus. Located in nucleus. Is expressed in several structures, including future brain; heart; liver; and nervous system. Orthologous to human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit hemolytic anemia, extramedullary hematopoiesis, and iron accumulation in the spleen, liver, and Kupffer cells. [provided by MGI curators] |