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Protein Coding Gene : Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3

Primary Identifier  MGI:1341723 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  16512
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables inward rectifier potassium channel activity. Involved in potassium ion transport. Located in plasma membrane. Is expressed in brain; genitourinary system; spinal cord; and submandibular gland. Orthologous to human KCNH3 (potassium voltage-gated channel subfamily H member 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal long term object recognition memory, spatial reference memory, spatial working memory, and long term potentiation. Mice homozygous for a different knock-out allele exhibit neuron hyperexcitability and seizures. [provided by MGI curators]
  • synonyms:
  • Elk2,
  • MGI:2146131,
  • AU019351,
  • ether a go-go like,
  • RIKEN cDNA C030044P22 gene,
  • MGI:1924786,
  • potassium voltage-gated channel, subfamily H (eag-related), member 3,
  • C030044P22Rik,
  • Melk2,
  • expressed sequence AU019351,
  • Kcnh3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For