| Primary Identifier | MGI:1858420 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 51812 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity and telomerase inhibitor activity. Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be located in several cellular components, including dendrite; nuclear lumen; and perikaryon. Predicted to be part of Ino80 complex; MLL1 complex; and NSL complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human MCRS1 (microspherule protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal blastocyst formation but fail to implant and show pre-implantation lethality with a severe reduction in inner cell mass and epiblast cell number but normal specification of the trophoblast and primitive endoderm. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
