Primary Identifier | MGI:95679 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 14555 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in glycerophosphate shuttle. Acts upstream of or within several processes, including cellular response to cAMP; gluconeogenesis; and positive regulation of glycolytic process. Located in mitochondrion. Is active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; liver; and nervous system. Orthologous to human GPD1 (glycerol-3-phosphate dehydrogenase 1). PHENOTYPE: Mice homozygous for a spontaneous mutation are viable and phenotypically normal but show loss of glycerol-3-phosphate dehydrogenase 1 activity in adult tissues. [provided by MGI curators] |