Primary Identifier | MGI:3611448 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 668218 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phospholipid binding activity. Predicted to be involved in several processes, including phagocytosis, engulfment; plasma membrane tubulation; and podosome assembly. Predicted to be located in anchoring junction; cell cortex; and cell projection. Predicted to be active in plasma membrane and podosome. Predicted to colocalize with phagocytic cup. Is expressed in liver and thymus primordium. Orthologous to human BIN2 (bridging integrator 2). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and healthy with no significant alterations in basic blood parameters. [provided by MGI curators] |