Primary Identifier | MGI:3646919 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 668225 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in microtubule severing and negative regulation of cell migration. Predicted to be located in cell leading edge. Orthologous to human FIGNL2 (fidgetin like 2). PHENOTYPE: Conditional knock-out in cultured adult dorsal root ganglion neurons results in longer axons and attenuated growth cone retraction in response to inhibitory molecules. [provided by MGI curators] |