| Primary Identifier | MGI:105062 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 110542 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including anti-Mullerian hormone receptor activity; protein homodimerization activity; and transforming growth factor beta receptor activity, type II. Acts upstream of or within sex differentiation. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including bone; early embryo; forebrain; genitourinary system; and spinal cord lumbar region. Used to study persistent Mullerian duct syndrome. Human ortholog(s) of this gene implicated in persistent Mullerian duct syndrome. Orthologous to human AMHR2 (anti-Mullerian hormone receptor type 2). PHENOTYPE: Homozygous null mutant males have a complete male reproductive tract, but also a uterus and oviducts. Functional sperm are produced, but most males are infertile because female reproductive organs block sperm transfer. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
