Primary Identifier | MGI:96195 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 15423 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables HMG box domain binding activity. Acts upstream of or within anterior/posterior pattern specification; cartilage development; and embryonic organ morphogenesis. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; embryo mesenchyme; nervous system; skin; and urinary system. Orthologous to human HOXC4 (homeobox C4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit some postnatal lethality (in the case of one allele but no the other), transformations of thoracic vertebrae, and abnormal rib attachment and sternebra morphology. [provided by MGI curators] |