Primary Identifier | MGI:1921424 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 74174 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable tRNA binding activity. Involved in piRNA-mediated gene silencing by mRNA destabilization and secondary piRNA processing. Located in cytoplasm. Is active in piP-body. Is expressed in gonad. Orthologous to human GTSF1 (gametocyte specific factor 1). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility due to arrested male meiosis and apoptosis of male germ cells. [provided by MGI curators] |