| Primary Identifier | MGI:1918313 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 71063 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system and genitourinary system. Orthologous to human ZNF597 (zinc finger protein 597). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality with a developmental arrest at the egg cylinder stage. Adult heterozygotes show ataxic or epileptic behaviors, spongiform pathology and neurodegeneration in the dorsal striatum and deep cortical layers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
