Primary Identifier | MGI:1924029 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 76779 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within axoneme assembly; embryonic morphogenesis; and smoothened signaling pathway. Located in centrosome; ciliary base; and ciliary tip. Part of intraciliary transport particle A and intraciliary transport particle B. Is expressed in several structures, including cranial ganglion; neural tube; olfactory epithelium; respiratory system; and thymus primordium. Orthologous to human CLUAP1 (clusterin associated protein 1). PHENOTYPE: Homozygous mutant mice exhibit mid-gestation lethality, failure of embryonic turning, enlarged pericardial sacs, neural tube defects and lack primary cilia. [provided by MGI curators] |