| Primary Identifier | MGI:1915265 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 68015 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide; protein folding; and translational attenuation. Located in mitochondrion. Is active in cell periphery. Is expressed in several structures, including adrenal gland; cerebral cortex; liver; metanephros epithelium; and white fat. Orthologous to human TRAP1 (TNF receptor associated protein 1). PHENOTYPE: Mice homozygous for a gene trap allele exhibit reduced body weight; liver and spleen hyperplasia; decreased chronic inflammation and tumor incidents; deregulated mitochondrial respiration; and increased oxidative stress. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
