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Protein Coding Gene : Vasn vasorin
Primary Identifier  MGI:2177651 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  246154
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transforming growth factor beta binding activity. Acts upstream of or within cellular response to hypoxia and cellular response to redox state. Located in mitochondrion and plasma membrane. Is expressed in several structures, including cardiovascular system; cranium; embryo mesenchyme; genitourinary system; and gut. Orthologous to human VASN (vasorin).
PHENOTYPE: Mice homozygous for a targeted allele exhibit increased sensitivity to TNFalpha-induced lethality, TNFalpha-, cycloheximide-, or CoCl2-induced cell death, and reduced male fertility. [provided by MGI curators]
  • synonyms:
  • Vasn,
  • RIKEN cDNA 2610528G05 gene,
  • vasorin,
  • MGI:1921457,
  • Slitl2,
  • Slit-like 2 (Drosophila),
  • 2610528G05Rik,
  • ATIA
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