Primary Identifier | MGI:109373 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 15369 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heme binding activity and heme oxygenase (decyclizing) activity. Predicted to be involved in porphyrin-containing compound catabolic process; response to hypoxia; and response to oxidative stress. Predicted to be located in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human HMOX2 (heme oxygenase 2). PHENOTYPE: Mice homozygous for disruptions in this gene are normal for the most part. However, they are sensitive to incrreases and decreases in oxygen levels and this results in some behavioral and nervous system response abnormalities. [provided by MGI curators] |