Primary Identifier | MGI:1913876 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 66626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable zinc ion binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to act upstream of or within apoptotic process and tumor necrosis factor-mediated signaling pathway. Predicted to be active in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. Is expressed in embryo; otic pit; and otocyst. Orthologous to human CDIP1 (cell death inducing p53 target 1). PHENOTYPE: Homozygous KO impairs (protects against) ER-stress-induced cell death in the liver. [provided by MGI curators] |