| Primary Identifier | MGI:2443582 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 268860 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; pyridoxal phosphate binding activity; and succinate-semialdehyde dehydrogenase binding activity. Predicted to contribute to 4-aminobutyrate:2-oxoglutarate transaminase activity. Involved in nervous system process. Located in mitochondrion. Is expressed in several structures, including ganglia; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease. Orthologous to human ABAT (4-aminobutyrate aminotransferase). PHENOTYPE: Mice with loss of expression in T cells show T cell differentiation abnormalities in vitro and decreased susceptibility to experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
