| Primary Identifier | MGI:3050795 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 239719 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity; actin binding activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including circulatory system development; liver development; and nervous system development. Located in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; intestine wall; and lung. Orthologous to human MRTFB (myocardin related transcription factor B). PHENOTYPE: Mice homozygous for knock-out alleles exhibit prenatal lethality with widespread hemorrhaging, cardiovascular defects, and craniofacial anomalies. Mice homozygous for a gene trap allele exhibit fetal lethality due to cardiac outflow tractdefects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
