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Protein Coding Gene : Bfar bifunctional apoptosis regulator
Primary Identifier  MGI:1914368 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  67118
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable caspase binding activity; protein-macromolecule adaptor activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of IRE1-mediated unfolded protein response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in central nervous system; heart valve; reproductive system; and urinary system. Orthologous to human BFAR (bifunctional apoptosis regulator).
  • synonyms:
  • 3010001A07Rik,
  • AW107665,
  • RIKEN cDNA 3010001A07 gene,
  • expressed sequence AW107665,
  • Bfar,
  • RNF47,
  • AI666707,
  • bifunctional apoptosis regulator,
  • expressed sequence AI666707,
  • MGI:2146480,
  • MGI:2146617
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