| Primary Identifier | MGI:1354388 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 50525 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Acts upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; plasma membrane bounded cell projection organization; and stress fiber assembly. Located in several cellular components, including cytoskeleton; lateral wall of outer hair cell; and sperm principal piece. Is expressed in cochlea. Orthologous to human SPAG6 (sperm associated antigen 6). PHENOTYPE: Many homozygotes for a targeted null mutation exhibit reduced growth, hydrocephaly, and lethality by 8 weeks of age. Surviving males have sperm defects and are infertile, while females show reduced fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
