| Primary Identifier | MGI:96529 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 16136 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Predicted to be located in endoplasmic reticulum and extracellular region. Predicted to be part of IgG immunoglobulin complex. Is expressed in bone marrow; embryo; lesser omentum; liver; and yolk sac. Human ortholog(s) of this gene implicated in agammaglobulinemia 2. Orthologous to several human genes including IGLL1 (immunoglobulin lambda like polypeptide 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit spleen hypoplasia, a leaky blockade of B cell development at the pre-B stage, and decreased IgG levels in response to a T-cell dependent antigen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
