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Protein Coding Gene : Ube2l3 ubiquitin-conjugating enzyme E2L 3
Primary Identifier  MGI:109240 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  22195
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ubiquitin conjugating enzyme activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; heart; immune system; lung; and reproductive system. Orthologous to human UBE2L3 (ubiquitin conjugating enzyme E2 L3).
PHENOTYPE: A portion of hypomorphic embyros die before birth while those that survive are growth retarded and do not survive past the first day of life. The embryonic and perinatal lethality are attributed to defective placental development. [provided by MGI curators]
  • synonyms:
  • UbcM4,
  • expressed sequence C79827,
  • ubiquitin-conjugating enzyme E2L 3,
  • Ubce7,
  • MGI:2146706,
  • C79827,
  • MGD-MRK-38285,
  • ubiquitin-conjugating enzyme 7,
  • Ube2l3
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Disease

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