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Protein Coding Gene : Aifm3 apoptosis-inducing factor, mitochondrion-associated 3
Primary Identifier  MGI:1919418 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  72168
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable oxidoreductase activity, acting on NAD(P)H. Predicted to be involved in execution phase of apoptosis. Located in mitochondrion. Is expressed in cerebellum and heart. Orthologous to human AIFM3 (AIF family member 3).
PHENOTYPE: Homozygous knock-out mice are viable and do not exhibit neural tube defects. Another null allele shows increased fasting glucose levels and circulating aspartate transaminase level with abnormal cholesterol homeostasis. [provided by MGI curators]
  • synonyms:
  • apoptosis-inducing factor, mitochondrion-associated 3,
  • Aifm3,
  • RIKEN cDNA 2810401C16 gene,
  • expressed sequence AI840249,
  • MGI:2146492,
  • AI840249,
  • 2810401C16Rik
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