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Protein Coding Gene : Tssk2 testis-specific serine kinase 2
Primary Identifier  MGI:1347559 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  22115
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables magnesium ion binding activity and protein serine/threonine kinase activity. Involved in peptidyl-serine phosphorylation and spermatid development. Located in acrosomal vesicle and centriole. Is expressed in embryo; seminiferous tubule; spermatid; and testis. Orthologous to human TSSK2 (testis specific serine kinase 2).
PHENOTYPE: Male mice homozygous for a knock-out allele of Tssk1 and 2 are infertile due to arrested spermatogenesis. [provided by MGI curators]
  • synonyms:
  • MGI:892906,
  • serine/threonine kinase 22B (spermiogenesis associated),
  • Stk22b,
  • testis-specific serine kinase 2,
  • Tsk2,
  • SPOGA2,
  • DGS-G,
  • testis specific serine/ threonine kinase 2,
  • Tssk2
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