| Primary Identifier | MGI:2136886 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 65079 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chondroitin sulfate binding activity; heparin binding activity; and neuregulin receptor activity. Involved in several processes, including negative regulation of neuron projection development; neuronal signal transduction; and regulation of postsynapse assembly. Acts upstream of or within axonogenesis. Located in several cellular components, including axonal growth cone; dendritic shaft; and neuronal cell body. Is active in glutamatergic synapse. Is expressed in several structures, including cardiovascular system; forelimb bud; intestine; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human RTN4R (reticulon 4 receptor). PHENOTYPE: Homozygous null mice display decreased exploration in new environment, impaired coordination, and improved recovery and rubrospinal axon regeneration following spinal cord injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
