Primary Identifier | MGI:1195461 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 18951 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GTPase activity; guanyl ribonucleotide binding activity; and protein homodimerization activity. Involved in adult behavior; regulation of synaptic vesicle docking; and social behavior. Located in cell cortex; synaptic vesicle; and terminal bouton. Part of septin complex. Is active in calyx of Held. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human SEPTIN5 (septin 5). PHENOTYPE: Mice homozygous for disruptions in this gene show no gross phenotypic changes. Partial defects in synaptic transmission is reported for one allele, and platelet secretion and modest behavioral defects reported for a different allele. [provided by MGI curators] |