| Primary Identifier | MGI:99430 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 15260 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and histone binding activity. Predicted to contribute to nucleosome binding activity. Acts upstream of or within gastrulation; muscle cell differentiation; and osteoblast differentiation. Located in chromatin. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; limb bud; and sensory organ. Orthologous to human HIRA (histone cell cycle regulator). PHENOTYPE: Homozygotes for a targeted null mutation exhibit disrupted gastrulation, malformations of axial and paraxial mesoendoderm, abnormal placentas, failure of cardiac development, and lethality by embryonic day 11. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
