Primary Identifier | MGI:1101356 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 107522 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to act upstream of or within peptide hormone processing. Predicted to be located in Golgi membrane; trans-Golgi network; and transport vesicle membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; heart; and nervous system. Orthologous to several human genes including ECE2 (endothelin converting enzyme 2). PHENOTYPE: Homozygous mutant mice develop normally, are viable and healthy, and exhibit normal fertility in both sexes, as well as a normal life span. [provided by MGI curators] |